BDBM50568544 CHEMBL4870529

SMILES CN(C)c1nccn2c(c(nc12)-c1ccc(F)cc1)-c1ccnc(N)n1

InChI Key InChIKey=JJUFPIADJDYDIT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50568544   

TargetCasein kinase I isoform epsilon(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK2/ cyclinA using histone H1 as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/ p25 expressed in bacterial expression system using histone H1 as substrate in presence of [gamma-33P]ATP by rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK9/CyclinT expressed in baculovirus infected Sf9 cells using YSPTSPSYSPTSPSYSPTSPSKKK as substrate in presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig brain GSK alpha/beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed