BDBM50568537 CHEMBL4861720

SMILES CN(C)c1nccn2c(-c3cnn(C)c3)c(nc12)-c1ccc(F)cc1

InChI Key InChIKey=KASWNWVAOVGTLI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50568537   

TargetCasein kinase I isoform epsilon(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK2/ cyclinA using histone H1 as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/ p25 expressed in bacterial expression system using histone H1 as substrate in presence of ATP measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK9/CyclinT expressed in baculovirus infected Sf9 cells using YSPTSPSYSPTSPSYSPTSPSKKK as substrate in presence of A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pig brain GSK alpha/beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of ATP measured after 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Nantes

Curated by ChEMBL
LigandPNGBDBM50568537(CHEMBL4861720)
Affinity DataIC50: 7.35E+3nMAssay Description:Inhibition of recombinant human HASPIN (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed