BDBM50568531 CHEMBL4855475

SMILES Fc1ccccc1CNC1CC11CCc2ccccc12

InChI Key InChIKey=RAPIPJBUMYLYKZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50568531   

TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568531(CHEMBL4855475)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568531(CHEMBL4855475)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568531(CHEMBL4855475)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568531(CHEMBL4855475)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human KDM1A (172 to 852 residues) using Bio-H3K4me2 peptide as substrate incubated for 1 hr by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568531(CHEMBL4855475)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MAO-A (unknown origin) by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568531(CHEMBL4855475)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of MAO-B (unknown origin) by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed