BDBM50568525 CHEMBL4859930

SMILES CCN(CC)S(=O)(=O)c1ccc(cc1)[C@H]1C[C@@H]1NC(=O)OC(C)(C)C

InChI Key InChIKey=NYGNRKAPDFSEJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568525   

TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568525(CHEMBL4859930)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human LSD1 expressed in Escherichia coli BL21 (DE3) cells using (ARTK(diMe)QTARKSTGGKAPRKQLA peptide as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568525(CHEMBL4859930)
Affinity DataIC50: 708nMAssay Description:Inhibition of MAO-A (unknown origin) preincubated for 20 mins using 5-hydroxytryptamine as substrate followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568525(CHEMBL4859930)
Affinity DataIC50: 655nMAssay Description:Inhibition of MAO-B (unknown origin) using benzylamine as substrate preincubated for 20 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed