BDBM50568524 CHEMBL4847919

SMILES CCN(CC)S(=O)(=O)c1ccc(cc1)[C@H]1C[C@@H]1N

InChI Key InChIKey=ZUPXTWCPGBCTFM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50568524   

TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568524(CHEMBL4847919)
Affinity DataIC50: 123nMAssay Description:Inhibition of human LSD1 expressed in Escherichia coli BL21 (DE3) cells using (ARTK(diMe)QTARKSTGGKAPRKQLA peptide as substrate incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568524(CHEMBL4847919)
Affinity DataIC50: 807nMAssay Description:Inhibition of MAO-A (unknown origin) preincubated for 20 mins using 5-hydroxytryptamine as substrate followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568524(CHEMBL4847919)
Affinity DataIC50: 898nMAssay Description:Inhibition of MAO-B (unknown origin) using benzylamine as substrate preincubated for 20 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568524(CHEMBL4847919)
Affinity DataIC50: 123nMAssay Description:Inhibition of KDM1A (unknown origin) incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568524(CHEMBL4847919)
Affinity DataIC50: 807nMAssay Description:Inhibition of recombinant MAO-A (unknown origin) using 5-hydroxytryptamine as substrate incubated for 20 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568524(CHEMBL4847919)
Affinity DataIC50: 898nMAssay Description:Inhibition of recombinant MAO-B (unknown origin) using benzylamine as substrate incubated for 20 mins followed by substrate addition measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed