BDBM50568480 CHEMBL4863099::US12122742, Compound I-d-4

SMILES OC(=O)CN(c1ccc(N(CC(O)=O)S(=O)(=O)c2ccc3OCOc3c2)c2ccccc12)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=QKEPIBLKFBKCOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568480   

TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50568480(CHEMBL4863099 | US12122742, Compound I-d-4)
Affinity DataIC50: 149nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM50568480(CHEMBL4863099 | US12122742, Compound I-d-4)
Affinity DataIC50: 149nMAssay Description:Fluorescence polarization assay was performed on a Wallac Victor 3V multi-label counter/plate reader (PerkinElmer, Shelton, CT) using 484 nm excitati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent