BDBM50568250 CHEMBL4847801

SMILES Cn1cc2cc(ccc2n1)-c1ccc(CN2Cc3ncsc3C2=O)c(F)c1

InChI Key InChIKey=XFZVUORXFGXXCR-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50568250   

TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50568250(CHEMBL4847801)
Affinity DataEC50:  2.00E+3nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine M1 receptor expressed in CHO cells in presence of acetylcholine at EC20 concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50568250(CHEMBL4847801)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine M2/Gqi5 receptor expressed in CHO cells in presence of acetylcholine at EC20 concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50568250(CHEMBL4847801)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine M3 receptor expressed in CHO cells in presence of acetylcholine at EC20 concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetComplement decay-accelerating factor(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50568250(CHEMBL4847801)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine M4/Gqi5 receptor expressed in CHO cells in presence of acetylcholine at EC20 concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50568250(CHEMBL4847801)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine M5 receptor expressed in CHO cells in presence of acetylcholine at EC20 concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed