BDBM50568218 CHEMBL4859382

SMILES CNC(=O)[C@H]1Cc2c(CN1C(=O)C[C@H]1CCCN(C1)C(=O)C=C)[nH]c1ccccc21

InChI Key InChIKey=JZCPISYHINOJCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568218   

TargetTyrosine-protein kinase BTK(Human)
X-Chem

Curated by ChEMBL
LigandPNGBDBM50568218(CHEMBL4859382)
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
X-Chem

Curated by ChEMBL
LigandPNGBDBM50568218(CHEMBL4859382)
Affinity DataIC50: 5.92E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK C481S mutant expressed in baculovirus infected in Sf9 cells incubated for 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed