BDBM50568184 CHEMBL4874861

SMILES CCCCN(CCCC)CCCOc1ccc(cc1)C(=O)c1c(CCCC)oc2ccc(NC(=O)Nc3ccc(cc3)C#N)cc12

InChI Key InChIKey=LPCIHHNABCQFQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50568184   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50568184(CHEMBL4874861)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated with compound for 1 hr fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed