BDBM50568120 CHEMBL4859414

SMILES Fc1cccc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCN(CC(F)(F)F)C[C@@H]3c3ccccc3)cc2F)n1

InChI Key InChIKey=WSTNZILNGXCYBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568120   

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50568120(CHEMBL4859414)
Affinity DataIC50: 700nMAssay Description:Inhibition of human Nav1.5 by automated voltage clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50568120(CHEMBL4859414)
Affinity DataIC50: 410nMAssay Description:Inhibition of human Nav1.5 VSD2 R814A mutant by automated voltage clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed