BDBM50567927 CHEMBL4859856

SMILES NC(=O)c1cccc(NC(=O)[C@@H](NC(=O)c2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)c2ccc(OCc3ccccc3)cc2)c1

InChI Key InChIKey=RNJZSKJJNTVURL-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567927   

TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50567927(CHEMBL4859856)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of NS2B-NS3 protease in DENV2proHeLa system assessed as inhibition of luciferase signal incubated for 24 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50567927(CHEMBL4859856)
Affinity DataKi:  6.30E+3nMAssay Description:Competitive inhibition of DENV2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda(DE3) using FRET substrate preincubated with enzyme for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed