BDBM50567734 CHEMBL4854964

SMILES N#CCCn1cc(cn1)-n1ccc2cnc3[nH]ccc3c12

InChI Key InChIKey=HYZULNNIBJFMSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567734   

TargetTyrosine-protein kinase JAK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50567734(CHEMBL4854964)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK1 (850 to 1154 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50567734(CHEMBL4854964)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N-terminal His-tagged JAK2 (826 to 1132 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed