BDBM50567392 CHEMBL4851776

SMILES ONC(=O)c1ccc(CN(CC(=O)NCc2ccccc2)C(=O)Cc2ccccc2)cc1

InChI Key InChIKey=YSVJWTMEMYMSTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567392   

TargetHistone deacetylase 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50567392(CHEMBL4851776)
Affinity DataIC50: 600nMAssay Description:Inhibition of C-terminal FLAG/His-tagged human recombinant HDAC1 (1 to 482 residues) expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50567392(CHEMBL4851776)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL (Z-Lys(Ac)-AMC) fluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed