BDBM50567342 CHEMBL4846377

SMILES CN1CCN(CC1)NC(=O)c1cccc(c1)C(=O)NO

InChI Key InChIKey=LLAPOEIECXFUIX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50567342   

TargetHistone deacetylase 8(Human)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human HDAC8 using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 750nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using fluorogenic substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of human HDAC6 using Z-Lys(Ac)-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 1.31E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50567342(CHEMBL4846377)
Affinity DataIC50: 7.11E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed