BDBM50567250 CHEMBL4848113

SMILES O=S(=O)(Oc1ccccc1)n1nc(cc1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=LKXGPKSQPCFXRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567250   

TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50567250(CHEMBL4848113)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant COX-2 assessed as production of PGE2 using arachidonic acid as a substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50567250(CHEMBL4848113)
Affinity DataIC50: 9.38E+3nMAssay Description:Inhibition of ovine COX-1 assessed as production of PGE2 using arachidonic acid as a substrate preincubated for 60 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed