BDBM50567242 CHEMBL4869842

SMILES Cc1cc(nn1S(=O)(=O)Oc1ccccc1I)-c1ccc(C)cc1

InChI Key InChIKey=DEPLDXFZWRLVPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567242   

TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50567242(CHEMBL4869842)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant COX-2 assessed as production of PGE2 using arachidonic acid as a substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50567242(CHEMBL4869842)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX-1 assessed as production of PGE2 using arachidonic acid as a substrate preincubated for 60 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed