BDBM50567241 CHEMBL4871081

SMILES Cc1cc(nn1S(=O)(=O)Oc1ccc(I)cc1)-c1ccc(C)cc1

InChI Key InChIKey=BHMJOOIJDGJQIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567241   

TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50567241(CHEMBL4871081)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human recombinant COX-2 assessed as production of PGE2 using arachidonic acid as a substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50567241(CHEMBL4871081)
Affinity DataIC50: 9.66E+4nMAssay Description:Inhibition of ovine COX-1 assessed as production of PGE2 using arachidonic acid as a substrate preincubated for 60 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed