BDBM50567219 CHEMBL4849978::US20250114338, Example 180

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1S(C)(=O)=O)c1ccc(OCCN2CC(CF)C2)cc1

InChI Key InChIKey=ALLRPIPLWLLBGX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567219   

TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50567219(CHEMBL4849978 | US20250114338, Example 180)
Affinity DataIC50: 11nMAssay Description:Displacement of fluorescein PGC1alpha from recombinant ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50567219(CHEMBL4849978 | US20250114338, Example 180)
Affinity DataEC50:  0.222nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent