BDBM50567039 CHEMBL4860700

SMILES C(Cn1nnc2ccc(cc12)-c1c[nH]c2ccccc12)N1CCNCC1

InChI Key InChIKey=RBVHLCAWUKSDHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567039   

TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567039(CHEMBL4860700)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567039(CHEMBL4860700)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells assessed as kynurenine concentration formation using L-tryptophan as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed