BDBM50567022 CHEMBL4875368

SMILES NC(=O)Cn1nnc2cc(ccc12)-c1c[nH]c2ccccc12

InChI Key InChIKey=WWMNIVQWMHWOTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567022   

TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567022(CHEMBL4875368)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567022(CHEMBL4875368)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells assessed as kynurenine concentration formation using L-tryptophan as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed