BDBM50567010 CHEMBL4847184

SMILES c1[nH]c2ccccc2c1-c1ccc2cncnc2c1

InChI Key InChIKey=RQHBSKLTBOAVOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567010   

TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567010(CHEMBL4847184)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567010(CHEMBL4847184)
Affinity DataIC50: 490nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells assessed as kynurenine concentration formation using L-tryptophan as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed