BDBM50566959 CHEMBL4846560

SMILES Nc1nc2cc(ccc2o1)-c1nn(CCCCCCC(=O)NO)c2ncnc(N)c12

InChI Key InChIKey=FKVKATMLAUBQFC-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50566959   

TargetSerine/threonine-protein kinase mTOR(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 231nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566959(CHEMBL4846560)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed