BDBM50566923 CHEMBL4855000

SMILES CCc1cc(Nc2nc(NCCc3ccccc3)nc3cccc(OC)c23)n[nH]1

InChI Key InChIKey=AUJIZOUNDSPWQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50566923   

TargetG protein-coupled receptor kinase 6(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50566923(CHEMBL4855000)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full-length human GRK6 using casein as substrate measured after 80 mins in presence of [gamma33P]ATP by radiometric scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50566923(CHEMBL4855000)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human Aurora A using LRRASLG as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometric sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50566923(CHEMBL4855000)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human IGF-1R (959 to end residues) using KKKSPGEYVNIEF as substrate incubated for 40 mins in presence of [gamma-33ATP] by r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed