BDBM50566796 CHEMBL4871581

SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(cc4c3N(C)C2=O)-c2cnn(C)c2)c1F

InChI Key InChIKey=BEIAIBOGYLFZCK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50566796   

LigandPNGBDBM50566796(CHEMBL4871581)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of VEGFR2 (unknown origin) incubated for 90 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566796(CHEMBL4871581)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of c-KIT (unknown origin) incubated for 90 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566796(CHEMBL4871581)
Affinity DataIC50: 1nMAssay Description:Inhibition of TRKA (unknown origin) incubated for 90 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50566796(CHEMBL4871581)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of AURKB (unknown origin) incubated for 90 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50566796(CHEMBL4871581)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of PDGFR-beta (unknown origin) incubated for 90 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed