BDBM50566652 CHEMBL4871228

SMILES [H][C@]12CS[C@@H](CCCCCC(=O)NC(=O)C(CNC(=O)C(NC3=NS(=O)(=O)c4ccccc34)C(C)C)NC(=O)C3(CC3)NC(=O)COc3ccccc3-c3n[nH]c4ccc(Cl)cc34)[C@@]1([H])NC(=O)N2

InChI Key InChIKey=CQCQNMJFDYVMFG-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50566652   

TargetApoptosis regulator Bcl-2(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50566652(CHEMBL4871228)
Affinity DataKd:  21nMAssay Description:Binding affinity to Bcl-2 (unknown origin) measured by surface plasmon resonance based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50566652(CHEMBL4871228)
Affinity DataKd:  96nMAssay Description:Binding affinity to Bcl-xl (unknown origin) measured by surface plasmon resonance based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50566652(CHEMBL4871228)
Affinity DataKd:  1.24E+3nMAssay Description:Binding affinity to Mcl-1 (unknown origin) measured by surface plasmon resonance based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed