BDBM50566611 CHEMBL4875203

SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1cc(C)on1)c1c(F)c(ccc21)C(C)(C)O

InChI Key InChIKey=UUPBDBBRDHXXDR-BMSJAHLVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566611   

TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50566611(CHEMBL4875203)
Affinity DataIC50: 2nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50566611(CHEMBL4875203)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed