BDBM50566610 CHEMBL4857742

SMILES Cc1cc(no1)[C@H](C1CCOCC1)n1c2cc(ccc2c2ncc(cc12)-c1c(C)nnn1C)C(C)(C)O

InChI Key InChIKey=WFFRALIRWDMZPW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50566610   

TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50566610(CHEMBL4857742)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of BRD4 (unknown origin) assessed as reduction in c-Myc expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed