BDBM50566604 CHEMBL4856923
SMILES COc1cc2CCN(CCNC(=O)c3ccc(C)c(Nc4nccc(n4)-c4ccco4)c3)Cc2cc1OC
InChI Key InChIKey=NSYBFCBVMIYRAL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50566604
Affinity DataIC50: 3.90E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 10000 nM by m...More data for this Ligand-Target Pair
Affinity DataEC50: 1.19E+3nMAssay Description:Reversal of P-gp-mediated adriamycin resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring adri...More data for this Ligand-Target Pair
Affinity DataIC50: 5.41E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 3.125 nM by m...More data for this Ligand-Target Pair
Affinity DataIC50: 5.51E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 12.5 nM by me...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 37.5 nM by me...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 75 nM by meas...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 250 nM by mea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 500 nM by mea...More data for this Ligand-Target Pair
Affinity DataIC50: 8.43E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 1250 nM by me...More data for this Ligand-Target Pair
Affinity DataIC50: 4.53E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 5000 nM by me...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 5 uM by measuri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 40000 nM by m...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 0.125 uM by mea...More data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 0.5 uM by measu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 0.75 uM by meas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 1.25 uM by meas...More data for this Ligand-Target Pair
Affinity DataIC50: 7.68E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 2 uM by measuri...More data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 3 uM by measuri...More data for this Ligand-Target Pair
Affinity DataIC50: 4.88E+3nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 4 uM by measuri...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 20 uM by measur...More data for this Ligand-Target Pair