BDBM50566148 CHEMBL4790740

SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc2cc[nH]c(=O)c2c1)C(F)(F)F

InChI Key InChIKey=WBIISZAFPJBGRK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566148   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50566148(CHEMBL4790740)
Affinity DataKi:  91nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of 30 nM capsaicin-induced calcium uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50566148(CHEMBL4790740)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed