BDBM50565843 CHEMBL4786963

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N(c1ccc2CCCN(c2c1)S(C)(=O)=O)S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=CMMGEZXYPRCOKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50565843   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50565843(CHEMBL4786963)
Affinity DataIC50: 9.86E+3nMAssay Description:Inhibition of NLRP3 in PMA-stimulated human THP-1 cells assessed as reduction in IL-1beta release pre-treated for 24 hrs followed by stimulation with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed