BDBM50565736 CHEMBL4792905

SMILES COc1ccccc1N1CCN(CCCCn2cc(CCCC(O)=O)c3ccccc23)CC1

InChI Key InChIKey=YZCQTZCKJQJPLF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565736   

TargetAlpha-1A adrenergic receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50565736(CHEMBL4792905)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human alpha1A receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50565736(CHEMBL4792905)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha1B receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50565736(CHEMBL4792905)
Affinity DataIC50: 189nMAssay Description:Antagonist activity at human alpha1D receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed