BDBM50565734 CHEMBL4797051

SMILES OC(=O)CCCc1cn(CCCCN2CCN(CC2)c2ccccc2Cl)c2ccccc12

InChI Key InChIKey=MCZZODFVQRRXCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565734   

TargetAlpha-1A adrenergic receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50565734(CHEMBL4797051)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha1A receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50565734(CHEMBL4797051)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha1B receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50565734(CHEMBL4797051)
Affinity DataIC50: 189nMAssay Description:Antagonist activity at human alpha1D receptor transfected in HEK293 cells co-transfected with Galpha16 assessed as reduction in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed