BDBM50565499 CHEMBL4799439

SMILES CN1CCN(CC1)c1cc(CN2CCC[C@H]2c2ncccc2C)nc(C)n1

InChI Key InChIKey=SJRFKTBEMQHUCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565499   

TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50565499(CHEMBL4799439)
Affinity DataIC50: 79nMAssay Description:Inhibition of APC-conjugated anti-human CXCR4 clone 12G5 binding to CXCR4 in human HPBALL cells measured after 3 hrs by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50565499(CHEMBL4799439)
Affinity DataIC50: 0.25nMAssay Description:Antagonist activity at CXCR4 in human CD4-positive T cells assessed as inhibition of CXCL12-induced cytosolic calcium flux preincubated for 20 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50565499(CHEMBL4799439)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG stably expressed in CHO cells at -80 mV holding potential measured after 4 mins by Qpatch electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed