BDBM50565373 CHEMBL4778697

SMILES Fc1ccc(cc1F)C(=O)Nc1cccc(CNC(=O)c2sc3ccccc3c2OCc2ccccc2)c1

InChI Key InChIKey=WHNQKJDANCNUSJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565373   

TargetSentrin-specific protease 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50565373(CHEMBL4778697)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human SNEP1 (419 to 644 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSentrin-specific protease 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50565373(CHEMBL4778697)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSentrin-specific protease 5(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50565373(CHEMBL4778697)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human SNEP5 (567 to 755 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed