BDBM50565357 CHEMBL4790106

SMILES Brc1ccc(cc1)C(=O)Nc1cccc(CNC(=O)c2sc3ccccc3c2OCc2ccccc2)c1

InChI Key InChIKey=LCDLZOQBIJTJLB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565357   

TargetSentrin-specific protease 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50565357(CHEMBL4790106)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant human SNEP1 (419 to 644 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSentrin-specific protease 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50565357(CHEMBL4790106)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant human SNEP2 (365 to 589 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSentrin-specific protease 5(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50565357(CHEMBL4790106)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of recombinant human SNEP5 (567 to 755 residues) expressed in Escherichia coli (DE3) cells using RanGAP-SUMO2 substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed