BDBM50565345 CHEMBL4778200

SMILES CN(C)C1CCN(CC1)C(=O)c1cccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)N2CCOCC2)c1

InChI Key InChIKey=DOSFSEODSLVZNT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50565345   

LigandPNGBDBM50565345(CHEMBL4778200)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50565345(CHEMBL4778200)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 as substrate measured after 45 mins in presence of ATP by LANCE Ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50565345(CHEMBL4778200)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50565345(CHEMBL4778200)
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50565345(CHEMBL4778200)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed