BDBM50565342 CHEMBL4788677

SMILES CN1CCN(CC1)C(=O)c1ccc2nc(Nc3ccc(cc3)-c3nc(nc(n3)N3CCOCC3)N3CCOCC3)[nH]c2c1

InChI Key InChIKey=WHMJTYCPNSWDLA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50565342   

LigandPNGBDBM50565342(CHEMBL4788677)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50565342(CHEMBL4788677)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 as substrate measured after 45 mins in presence of ATP by LANCE Ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50565342(CHEMBL4788677)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50565342(CHEMBL4788677)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
LigandPNGBDBM50565342(CHEMBL4788677)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed