BDBM50565334 CHEMBL4786662

SMILES NC(=O)[C@@H]1CCCN1C(=O)c1ccc2nc(Nc3ccc(cc3)-c3nc(nc(n3)N3CCOCC3)N3CCOCC3)[nH]c2c1

InChI Key InChIKey=CWWWLWINFJYDAB-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565334   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Guizhou Medical University

Curated by ChEMBL

LigandBDBM50565334(CHEMBL4786662)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/30/2022
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
Guizhou Medical University

Curated by ChEMBL

LigandBDBM50565334(CHEMBL4786662)Copy SMILESCopy InChI

Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 as substrate measured after 45 mins in presence of ATP by LANCE Ultra assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/30/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL