BDBM50565312 CHEMBL4783133

SMILES COc1cc(ccc1[C@@H](O)c1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccc(cc1)C#N

InChI Key InChIKey=UHMLHIRSNCDVOO-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50565312   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565312(CHEMBL4783133)
Affinity DataEC50:  1.25E+3nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565312(CHEMBL4783133)
Affinity DataEC50:  438nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565312(CHEMBL4783133)
Affinity DataEC50:  507nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565312(CHEMBL4783133)
Affinity DataEC50:  5.81E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565312(CHEMBL4783133)
Affinity DataEC50:  196nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed