BDBM50565311 CHEMBL4795242

SMILES COc1cc(ccc1C(O)c1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccc(cc1)C#N

InChI Key InChIKey=UHMLHIRSNCDVOO-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50565311   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565311(CHEMBL4795242)
Affinity DataEC50:  113nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565311(CHEMBL4795242)
Affinity DataEC50:  13nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565311(CHEMBL4795242)
Affinity DataEC50:  32nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565311(CHEMBL4795242)
Affinity DataEC50:  3.00E+6nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50565311(CHEMBL4795242)
Affinity DataEC50:  7.40nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed