BDBM50565306 CHEMBL4800232

SMILES COc1cc(F)cc(CNc2ccc3[nH]nc(\C=C\c4ccccn4)c3c2)c1

InChI Key InChIKey=WIVNLRJLMBFTMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565306   

TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565306(CHEMBL4800232)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of TrkA (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565306(CHEMBL4800232)
Affinity DataIC50: 27nMAssay Description:Inhibition of TrkB (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565306(CHEMBL4800232)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of TrkC (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed