BDBM50565294 CHEMBL4777099

SMILES Fc1cc(F)cc(OCc2ccc3[nH]nc(\C=C\c4ccccn4)c3c2)c1

InChI Key InChIKey=IJEQTEVIXYPEPD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565294   

TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565294(CHEMBL4777099)
Affinity DataIC50: 21nMAssay Description:Inhibition of TrkA (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565294(CHEMBL4777099)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of TrkB (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50565294(CHEMBL4777099)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of TrkC (unknown origin) using Tyr1 peptide as substrate in presence of ATP measured after 2 hrs by FRET-based Z-Lyte kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed