BDBM50565253 CHEMBL4793377

SMILES COCCOCOC(=O)c1coc2ccc(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc34)cc12

InChI Key InChIKey=SGVIYGVVOOCNSC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565253   

TargetG-protein coupled bile acid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50565253(CHEMBL4793377)
Affinity DataEC50:  82nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50565253(CHEMBL4793377)
Affinity DataEC50:  211nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter incubated for 5.5 hrs and measured by Steady Glow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed