BDBM50565202 CHEMBL4776078

SMILES CCC(C)c1ccc(NC(=O)CCCCN2CCN(CC2)c2ccccc2OC)cc1

InChI Key InChIKey=IENGJXPNDVZIHT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50565202   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565202(CHEMBL4776078)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of recombinant human PDE4B expressed in Sf9 cells measured after 10 mins by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565202(CHEMBL4776078)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of recombinant human PDE7A expressed in Sf9 cells measured after 10 mins by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565202(CHEMBL4776078)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565202(CHEMBL4776078)
Affinity DataKi:  323nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed