BDBM50565196 CHEMBL4791316

SMILES COc1ccccc1N1CCN(CCCC(=O)Nc2ccc(cc2)C(C)(C)C)CC1

InChI Key InChIKey=ZYJPVZKDGSDKGS-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50565196   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565196(CHEMBL4791316)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of recombinant human PDE4B expressed in Sf9 cells measured after 10 mins by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565196(CHEMBL4791316)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant human PDE7A expressed in Sf9 cells measured after 10 mins by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565196(CHEMBL4791316)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50565196(CHEMBL4791316)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed