BDBM50565135 CHEMBL4777961

SMILES CCCCCCCCCCCCCCCCNNC(=O)c1cccs1

InChI Key InChIKey=HSHXDCVZWHOWCS-UHFFFAOYSA-N

Data  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50565135   

TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 370nMAssay Description:Inhibition of full length human recombinant HDAC11 (1 to 347 end residues) expressed in Sf9 cells using AcetylETDKmyr-AMC as substrate preincubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 830nMAssay Description:Inhibition of human full length C-terminal Flag tagged HDAC11 expressed in HEK293T cells assessed as reduction in demyristoylation activity using H3K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 830nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in ELISA cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC11 transfected in HEK293T cells using Ac-ETDKrnyr-AMC as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 830nMAssay Description:Inhibition of FLAG tagged full length human HDAC11 expressed in HEK293T cells using acyl-H3K9 peptide as substrate preincubated with compound for 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length C-terminal Flag tagged HDAC1 expressed in HEK293T cells using H3K9-myristoyl peptide as substrate by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length C-terminal Flag tagged HDAC4 expressed in HEK293T cells using H3K9-myristoyl peptide as substrate by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 7.76E+4nMAssay Description:Inhibition of N-terminal GST-tagged full length human recombinant HDAC6 (1 to 1215 end residues) expressed in Sf9 cells using Boc-Lys-(acetyl)-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 9.25E+4nMAssay Description:Inhibition of C-terminal 6xHis/FLAG-tagged full length human recombinant HDAC1 (1 to 482 end residues) expressed in Sf9 cells using Boc-Lys-(acetyl)-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC8 (1 to 377 end residues) expressed in Sf9 cells using Boc-Lys-(trifluoroacetyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged C-terminal His-tagged human HDAC4 (627 to 1084 end residues) expressed in baculovirus expression system in Sf9 ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FLAG tagged full length human HDAC1 expressed in HEK293T cells using acyl-H3K9 peptide as substrate preincubated with compound for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FLAG tagged full length human HDAC4 expressed in HEK293T cells using acyl-H3K9 peptide as substrate preincubated with compound for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FLAG tagged full length human HDAC8 expressed in HEK293T cells using acyl-H3K9 peptide as substrate preincubated with compound for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of East Anglia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50565135BDBM50565135(CHEMBL4777961)
Affinity DataIC50: 1.00E+5nMAssay Description:Agonistic activity in CHO-hFSHR cell-based cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed