BDBM50565053 CHEMBL4790157
SMILES COc1ccc(cc1)-c1cc(OC(C)=O)c2c(c(NC(=O)c3cccc(F)c3)oc2c1)-c1cccs1
InChI Key InChIKey=FFSYPDOYYMJFKT-UHFFFAOYSA-N
Data 24 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50565053
Affinity DataIC50: 5.40nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 5 uM measured...More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 2.5 uM measur...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of ABCB1 in human KB-VIN cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measur...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 5 uM measure...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 2.5 uM measu...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measure...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of ABCB1 in human HeLa S3 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measure...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Affinity DataIC50: 504nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
Affinity DataIC50: 559nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorub...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
Affinity DataIC50: 621nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitax...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of human full-length ABCB1 expressed in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincris...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 5 uM measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 2.5 uM measured...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 5 uM measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 2.5 uM measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ABCB1 in FLp-In-293 cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristine IC50 at 5 uM measured a...More data for this Ligand-Target Pair