BDBM50564923 CHEMBL4788940

SMILES Cc1cc2cc(NS(=O)(=O)Cc3ccc(cc3)C(=O)NO)ccc2n(C)c1=O

InChI Key InChIKey=KMSCXGNJNWHVIP-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564923   

TargetHistone deacetylase 1(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564923(CHEMBL4788940)
Affinity DataIC50: 545nMAssay Description:Inhibition of recombinant human HDAC1 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564923(CHEMBL4788940)
Affinity DataIC50: 152nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564923(CHEMBL4788940)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPeregrin(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50564923(CHEMBL4788940)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to BRPF1 (unknown origin) by Isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed