BDBM50564711 CHEMBL4791249

SMILES C=CC(=O)Nc1cccc(Nc2ncnc(Nc3ccc(cc3)C(=O)N3CCCCC3)n2)c1

InChI Key InChIKey=PIDFACDPHSZEFT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50564711   

TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564711(CHEMBL4791249)
Affinity DataIC50: 21nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564711(CHEMBL4791249)
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFR (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564711(CHEMBL4791249)
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of ITK (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564711(CHEMBL4791249)
Affinity DataIC50: 594nMAssay Description:Inhibition of BLK (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564711(CHEMBL4791249)
Affinity DataIC50: 524nMAssay Description:Inhibition of SRC (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50564711(CHEMBL4791249)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of BTK in human TMD8 cells assessed as reduction in cell proliferation incubated for 24 hrs by CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed