BDBM50564641 CHEMBL4798858

SMILES Fc1cccc(c1)C(=O)N1CCN(CC(=O)N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)CC1

InChI Key InChIKey=GFQZJWNHSQDLBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564641   

TargetAcetylcholinesterase(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564641(CHEMBL4798858)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasma AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50564641(CHEMBL4798858)
Affinity DataIC50: 6.90E+4nMAssay Description:Displacement of [3H]paroxetine from human SERT expressed in human HEK293 cells incubated for 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed